Pericardial Fat, Intrathoracic Fat, and Measures of Left Ventricular Structure and Function

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Pericardial fat, intrathoracic fat, and measures of left ventricular structure and function: the Framingham Heart Study.

BACKGROUND Pericardial fat has been implicated in the pathogenesis of obesity-related cardiovascular disease. Whether the associations of pericardial fat and measures of cardiac structure and function are independent of the systemic effects of obesity and visceral adiposity has not been fully explored. METHODS AND RESULTS Participants from the Framingham Heart Study (n=997; 54.4% women) under...

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Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study.

AIMS The aim of this study was to assess whether pericardial fat, intrathoracic fat, and visceral abdominal adipose tissue (VAT) are associated with the prevalence of cardiovascular disease (CVD). METHODS AND RESULTS Participants from the Framingham Heart Study Offspring cohort underwent abdominal and chest multidetector computed tomography to quantify volumes of pericardial fat, intrathoraci...

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Pericardial Fat and Echocardiographic Measures of Cardiac Abnormalities

OBJECTIVE Pericardial adipose tissue (PAT), a regional fat depot adjacent to the myocardium, may mediate the complex relation between obesity and cardiac left ventricular (LV) abnormalities. We sought to evaluate the association of PAT with echocardiographic measures of LV abnormalities in the Jackson Heart Study (JHS). RESEARCH DESIGN AND METHODS A total of 1,414 African Americans (35% men; ...

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Relation of regional fat distribution to left ventricular structure and function.

BACKGROUND The relation of body fat distribution to left ventricular (LV) structure and function is poorly defined. METHODS AND RESULTS A total of 2710 participants without heart failure or LV dysfunction in the Dallas Heart Study underwent dual energy x-ray absorptiometry and MRI assessment of fat distribution, LV morphology, and hemodynamics. Cross-sectional associations of fat distribution...

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ژورنال

عنوان ژورنال: Circulation

سال: 2009

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.108.828970